Rob DeRubeis is the Samuel H. Preston Term Professor in the Social Sciences and Professor of Psychology in the School of Arts and Sciences at the University of Pennsylvania. He has served on Penn’s faculty since receiving his doctorate in clinical psychology from the University of Minnesota in 1983. He has authored or co-authored over 150 articles and book chapters on topics that center on the treatment of depression. He has received career awards for his research contributions from the Society for Psychotherapy Research and the Association for Psychological Science. His empirical research comparing the benefits of cognitive therapy and medications for severe depression, published in the American Journal of Psychiatry and the Archives of General Psychiatry, has been the subject of media reports in The Economist, the Wall Street Journal, and USA Today. He has spoken about his work on podcasts and radio and television news programs, as well as to the Congressional Biomedical Research Caucus in Washington, DC. His current research brings “precision medicine” to mental health care, using actuarial methods to guide each patient to the treatment that is most likely to help them.